A New Phase in
Cell Delivery

High Throughput Screening has revolutionised drug discovery and biochemical research by enabling rapid evaluation of vast compound libraries and functional genomics screens to identify promising candidates for further development. Despite its power, HTS still faces challenges, such as drug solubility, effective cell delivery, and high costs. BubbleFect is simple to use, room temperature stable cell delivery vehicles for a wide variety of cargos, including large macromolecules (DNA, RNA, protein, CRISPR, etc) and furthermore can act as a suitable solvent environment for otherwise insoluble small molecule drugs.

Functional genomics seeks to decode gene functions and interactions by manipulating gene expression across a range of cell types. BubbleFect advances this field by offering superior transfection efficiency, low cytotoxicity, compatibility with various nucleic acids, and stability at room temperature. These features enable researchers to carry out more reliable, scalable, and high-throughput gene modulation studies, accelerating discoveries in disease mechanisms and therapeutic development.

BubbleFect uses molecular condensates; membrane-less compartments formed through phase separation. BubbleFect is emerging as powerful enhancer for CRISPR genome editing. By concentrating CRISPR components, improving specificity, and enabling programmable control, BubbleFect unlocks new applications in gene therapy, functional genomics, and synthetic biology. This innovative fusion of technologies offers a pathway to more efficient, targeted, and responsive genome engineering.