Non viral cell delivery

Join our FREE Alpha Program

Alpha Program. Deadline: 31 Aug 2025

  • When you join the FREE BubbleFect Alpha Program we set up a quick call to explore how our delivery technology can accelerate your research and answer questions about your application. We will take a few simple details like name, address, VAT number and prefered delivery date to send you your free BubbleFect*.

  • Using BubbleFect is refreshingly simple. Just mix your biological cargo, whether it's RNA, DNA, or protein, with BubbleFect reagent in water. Then, add your standard physiological buffer (e.g. PBS or cell culture medium) to set off the spontaneous bubble reaction, making it instantaneously ready to add to your cells!

  • A typical BubbleFect experiment fits easily into your standard lab schedule. After mixing your cargo with water and adding the BubbleFect reagent, add physiological buffer to get your formulation ready in minutes. Simply apply it to your cells and incubate, no media change or special handling required. Depending on your assay, you can begin to see results in as little as 30 minutes (to track directly labelled cargos) to 12 hours (for protein expression), whether you're tracking fluorescent nucleic acid or protein cargos, mRNA translation, DNA transfection or functional protein activity. Readouts can be observed via microscopy, flow cytometry, or standard plate-based assays, making integration seamless with your existing workflows.

  • At PartitionBio, we’re committed to supporting your success every step of the way. After you’ve had time to run your experiment with BubbleFect, our team will check in to hear about your results, answer any questions, and discuss how the platform performed in your specific application. We’re eager to explore opportunities for further experiments, optimisations, or potential collaborations to help you maximise the impact of your research. Your feedback guides our development, and together we can advance innovative solutions tailored to your scientific goals.

* Deadline to join: 31 August 2025

BubbleFect offers a gentle, easy-to-use alternative for intracellular delivery. Microscopic view of a blue cell surface covered with numerous yellow spherical droplets.

Join our Free Alpha Program

and get your FREE BubbleFect

BubbleFect is a room-temperature stable platform. Close-up view of numerous small blue bubbles suspended in a liquid against a blue background.
non-viral, room-temperature stable delivery platform. Colored microscope image showing a blue cell covered with numerous green droplets of BubbleFect.

BubbleFect

Seamless cell delivery, as easy as A, B, C!

  • A – Assemble

    Mix your cargo with BubbleFect in water – done.
    Simply combine your nucleic acid or protein cargo with BubbleFect. Mix by pipetting or vortexing.
    💡 First-time users can run a quick titration to optimise for their system.

  • B – Bubbles

    Add serum-free medium to instantly create Bubbles.
    Pipette in serum-free medium – Bubbles form on contact. The solution turns cloudy and is ready to use, no incubation needed.

  • C – Cells

    Transfer Bubbles onto your cells – that’s it.
    Add equal volume of Bubbles to cells. Incubate for 1 hour. Optional: wash cells in rich medium and proceed with your standard assay protocol.

Why it works

BubbleFect integrates into existing protocols with no disruption. It’s fast, compatible, and requires little optimisation, making high-efficiency delivery accessible for any lab.

FULL PROTOCOL